Acute promyelocytic leukaemia (APL)
APL is a type of blood cancer that affects cells called promyelocytes, which are white blood cells at an early stage of development.
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What is APL?
Acute promyelocytic leukaemia (APL) happens when the promyelocytes (a type of blood cell) don’t fully develop and become cancerous.
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Symptoms of APL
People with APL may experience blood clots, extreme tiredness, weight loss, unexplained bruising and recurring infections.
Discover the symptoms
![A researcher puts test tubes containing blood into a rack](https://bcuk.cdn.ngo/images/multiple_test_tubes_B7OVuTj.2e16d0ba.fill-512x275.jpg)
Tests to diagnose APL
If doctors think you might have APL, you'll have a series of tests. Doctors will look at your blood, bone marrow and genes.
More about testing
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APL treatment and side effects
APL develops quickly, so fast diagnosis and treatment are really important.
Treatment for APL
![Doctor with a stethoscope around their neck talks to patient about their blood cancer.](https://bcuk.cdn.ngo/images/doctor_and_patient_talking_resized.2e16d0ba.fill-512x275.jpg)
APL prognosis
Most people with APL respond well to treatment and have a good prognosis (outlook).
Your prognosis
![A family preparing a meal together](https://bcuk.cdn.ngo/images/RS13003_.2e16d0ba.fill-512x275.jpg)
Information for family and friends
If someone you love has been diagnosed with APL, you might find our information for family and friends helpful.
Read our information
Thank you to Consultant Haematologists Dr Richard Dillon, Dr Steven Knapper and Professor David Grimwade, as well as Research Nurse Anita Immanuel for checking our information on APL.