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Finding new ways to treat MPN

In this project, Dr Mishto wants to understand whether we might be able to harness our immune system to treat MPN.

The challenge

Myeloproliferative neoplasm (MPN) is a type of blood cancer that is rarely curable and can sometimes progress into an aggressive type of blood cancer called acute myeloid leukaemia. Whilst people can live many years with MPN, their quality of life is often reduced compared to someone without MPN and there’s a need to produce kinder and more effective treatments for these people.

The project

Dr Mishto and his team know that getting the number of cancerous cells in the blood below a certain level can significantly improve the quality of life for people with MPN, and he wants to find new ways to treat the disease that does this. His team are going to study whether we can use treatments that harness our own immune system to do this and to destroy MPN cells.

The future

This project could lead to new treatments being developed for MPN which are more effective and improve people’s quality of life. Ultimately, this would give people with MPN the best possible chance of survival.

What our community think

“I found this project investigates an important aspect of blood cancer.”

- Patient Voice Grant Advisory Network Member, living with an MPN