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Myelofibrosis (MF)

Myelofibrosis is a type of blood cancer that causes scar tissue to form in your bone marrow (the spongy material inside some of your bones, where blood cells are made).

Myelofibrosis at a glance

Myelofibrosis is a type of blood cancer. It belongs to a group of conditions that affect the blood called myeloproliferative neoplasms (MPN).

Myelofibrosis happens when scar tissue builds up in your bone marrow (the soft spongy material inside some of your bones, where blood cells are made). This stops your blood cells from developing properly.

Find out more about myelofibrosis and its causes

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People with myelofibrosis may experience breathlessness, unusual bleeding and bruising.

Another common symptom is a reduced ability to fight infection. Your GP may send you for blood tests to confirm a diagnosis.

Find out more about the symptoms and diagnosis of myelofibrosis

The treatment you have will depend on certain factors, including your blood counts, the symptoms you have and how fit you are. Some people don’t need treatment straight away.

Find out about treatment and side effects for myelofibrosis

Prognosis (outlook) can vary and will depend on how slowly or quickly the myelofibrosis is developing. Your prognosis is individual to you and your healthcare team can give you the best information.

Find out more about the prognosis for myelofibrosis

Clinical trials are how we find new treatments and improve current ones. We can help you find out about clinical trials for myelofibrosis. Even if you just want to know a bit more about myelofibrosis research, try our Clinical Trials Support Service.

Our previous research has focused on improving treatments for blood cancers. Read about our research impact.

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