74 results found.
Understanding how Adult T-cell lymphoma develops - Dr Goedele Maertens
In this project, Dr Maertens wants to understand how a virus can cause a rare type of lymphoma.
Understanding how MPN develops
In this project, Professor Hitchcock wants to understand more about how MPN develops.
Finding new ways to identify and treat the most aggressive type of DLBCL- Dr Dinis Calado
In this project, Dr Calado will try and understand more about why some types of DLBCL stop responding to treatment.
Understanding what causes relapse in people with AML - Professor Dominique Bonnet
In this project, Professor Bonet wants to understand more about the cell that she thinks is responsible for AML returning.
Understanding how some cancer cells are shielded from chemotherapy - Dr Ingo Ringhausen
In the project, Dr Ringhausen wants to understand more about how CLL cells can resist treatment.
Finding new ways to treat lymphoma - Dr Daniel Hodson
In this project, Dr Hodson is looking for new ways to treat non-Hodgkin lymphoma.
Understanding how fat cells are involved in myeloma returning - Professor Claire Edwards
In this project, Professor Claire Edwards will look at how fat cells are involved in myeloma progressing.
Understanding how CLL progresses - Dr Robbert Hoogeboom
In this project, Dr Hoogeboom wants to know more about how CLL cells move around the body and start growing.
Understanding the role of mutations in the blood as we get older
We are more likely to develop blood cancers as we get older. Dr Kirschner is trying to identify mutations that occur in our blood cells so people at risk of developing blood cancer can be monitored.
Using ‘fingerprints’ to understand the best ways to treat chronic lymphocytic leukaemia and diffuse large B-cell lymphoma
Chronic lymphocytic leukaemia (CLL) and diffuse large B-cell lymphoma (DLBCL) are blood cancers that have differences within and between each person. Professor Pepper wants to understand the specific features that cause these blood cancer cells to grow out of control and to understand why some cells aren’t destroyed by current treatments.
Finding new and better ways to treat leukaemia in babies
Childhood leukaemias are often caused by an alteration of a specific gene. As this type of leukaemia is difficult to treat and often comes back, new and better treatments need to be developed.
Making CAR-T cell therapy more effective for people with T-cell acute lymphoblastic leukaemia (T-ALL)
T-cell acute lymphoblastic leukaemia (T-ALL) is an aggressive type of blood cancer with few effective treatments available. Dr Paul Maciocia is working to make CAR-T cell therapy a more effective treatment for people with this disease.
A new treatment for myeloma
Myeloma is a blood cancer of the plasma cells which is difficult to treat. Dr Alanna Green is testing a new drug called karonudib which she hopes will be effective in treating myeloma.
Using CAR-T cell techniques to treat myelofibrosis
Myelofibrosis can require treatment via a stem cell transplant which involves intensive chemotherapy that can cause severe side effects and complications. CAR-T cell techniques provide an alternative and potentially less harmful treatment for young people affected by this disease.
Understanding the molecules that help myeloma cells to grow and survive
Professor Karadimitris has identified molecules that work together to cause myeloma cancer cells to grow in numbers and survive. He wants to understand more about how they do this so he can design and develop a new treatment for people with myeloma.
Finding new ways to treat chronic myeloid leukaemia (CML)
Most people with CML have a protein called BCR-ABL switched on inside their cells which causes the growth of cancer cells. In this project, Dr Oberoi and her team want to understand more about this protein to see if they can find ways to switch it off.
Finding new ways to treat acute myeloid leukaemia
Acute myeloid leukaemia (AML) is a type of blood cancer that is very difficult to treat. In this project, the team are trying to find new ways to treat the disease.
Using data to understand more about blood cancer
Real world data can tell us a lot about how treatments are working for people with blood cancer and what gaps exist. This study will look at data on 700,000 people affected by blood cancer to do just this.
Understanding more about the alterations in our cells that can cause myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML)
Myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML) are both types of blood cancer that can occur when the process which repairs damaged blood cells goes wrong. Dr Quek wants to understand more about this to develop better treatments for people with these diseases.
Improving the diagnosis of myeloproliferative neoplasms (MPN)
Diagnosing myeloproliferative neoplasms currently relies on bone marrow biopsy and the human eye. In this project, researchers will look for new, more accurate ways to diagnose the disease.